InVivoSIM anti-human NGF (Tanezumab Biosimilar)

Clone Tanezumab
Catalog # SIM0017
Category InVivoSIM™ Biosimilar Antibodies
Price
Size Regular Price
1mg $ 217.00
5mg $ 843.00
25mg $ 2,942.00
50mg $ 4,229.00
100mg $ 7,526.00
About InVivoSIM anti-human NGF (Tanezumab Biosimilar)

This non-therapeutic biosimilar antibody uses the same variable regions from the therapeutic antibody Tanezumab making it ideal for research use. This Tanezumab biosimilar reacts with human nerve growth factor (NGF), a neurotrophic factor involved in the regulation of growth, maintenance, proliferation, and survival of certain neurons. NGF is essential for the development and phenotypic maintenance of neurons in the peripheral nervous system (PNS) and for the functional integrity of cholinergic neurons in the central nervous system (CNS). Tanezumab was developed against nerve growth factor as a treatment for pain via a novel mechanisms different from conventional pain-killer drugs. 

InVivoSIM anti-human NGF (Tanezumab Biosimilar) Specifications
IsotypeHuman IgG2, κ
Recommended Isotype Control(s)InVivoPlus human IgG2 isotype control
Recommended Dilution BufferInVivoPure pH 7.0 Dilution Buffer
Mutations_
ImmunogenHuman NGF
Reported ApplicationsNGF neutralization
ELISA
FormulationPBS, pH 7.0
Contains no stabilizers or preservatives
Endotoxin<1EU/mg (<0.001EU/μg)
Determined by LAL gel clotting assay
Aggregation<5%
Determined by DLS
Purity>95%
Determined by SDS-PAGE
Sterility0.2 μM filtered
ProductionPurified from cell culture supernatant
PurificationProtein A
Molecular Weight150 kDa
Murine Pathogen TestsEctromelia/Mousepox Virus: Negative
Hantavirus: Negative
K Virus: Negative
Lactate Dehydrogenase-Elevating Virus: Negative
Lymphocytic Choriomeningitis virus: Negative
Mouse Adenovirus: Negative
Mouse Cytomegalovirus: Negative
Mouse Hepatitis Virus: Negative
Mouse Minute Virus: Negative
Mouse Norovirus: Negative
Mouse Parvovirus: Negative
Mouse Rotavirus: Negative
Mycoplasma Pulmonis: Negative
Pneumonia Virus of Mice: Negative
Polyoma Virus: Negative
Reovirus Screen: Negative
Sendai Virus: Negative
Theiler’s Murine Encephalomyelitis: Negative
StorageThe antibody solution should be stored at the stock concentration at 4°C. Do not freeze.
Application References