Clone | BVD2-23B6 | ||||||||||||
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Catalog # | BE0384 | ||||||||||||
Category | InVivoMab Antibodies | ||||||||||||
Price |
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The BVD2-23B6 monoclonal antibody reacts with human granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2). GM-CSF is a 14 kDa monomeric hematopoietic factor secreted by macrophages, T cells, mast cells, NK cells, endothelial cells, and fibroblasts. GM-CSF stimulates stem cells to differentiate into granulocytes (neutrophils, eosinophils, and basophils) and monocytes. The BVD2-23B6 antibody has been reported as a neutralizing antibody.
Isotype | Rat IgG2a, κ |
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Recommended Isotype Control(s) | InVivoMAb rat IgG2a isotype control, anti-trinitrophenol |
Recommended Dilution Buffer | InVivoPure pH 7.0 Dilution Buffer |
Mutations | D265A |
Immunogen | Recombinant human GM-CSF |
Reported Applications | in vitro GM-CSF neutralization ELISA |
Formulation | PBS, pH 7.0 Contains no stabilizers or preservatives |
Endotoxin | <2EU/mg (<0.002EU/μg) Determined by LAL gel clotting assay |
Purity | >95% Determined by SDS-PAGE |
Sterility | 0.2 µm filtration |
Production | Purified from tissue culture supernatant in an animal free facility |
Purification | Protein G |
Molecular Weight | 150 kDa |
Storage | The antibody solution should be stored at the stock concentration at 4°C. Do not freeze. |