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[#BE0328]InVivoMAb anti-mouse CD28

관리자 2020-03-12 Views 1,887

About InVivoMAb anti-mouse CD28

The D665 monoclonal antibody reacts with mouse CD28, a 45 kDa costimulatory receptor and a member of the Ig superfamily. CD28 is expressed by thymocytes, most peripheral T cells, and NK cells. CD28 is a receptor for CD80 (B7-1) and CD86 (B7-2). Signaling through CD28 induces IL-2 and IL-2 receptor expression and T cell proliferation. The D665 antibody is a CD28 superagonist and is most commonly used to induce the expansion of Treg cells in vivo in various mouse models of disease.

InVivoMAb anti-mouse CD28 Specifications

Isotype

Mouse IgG1, κ

Recommended Isotype Control(s)InVivoMAb mouse IgG1 isotype control, unknown specificity(BE0083)
Recommended InVivoPure Dilution BufferInVivoPure pH 7.0 Dilution Buffer(IP0070)
Immunogen

A20 cells expressing mouse CD28 and a recombinant mouse CD28-Ig fusion protein

Reported Applications
  • in vivo T cell stimulation/activation
  • in vitro T cell stimulation/activation
Formulation
  • PBS, pH 7.0
  • Contains no stabilizers or preservatives
Endotoxin
  • <2EU/mg (<0.002EU/μg)
  • Determined by LAL gel clotting assay
Purity
  • >95%
  • Determined by SDS-PAGE
Sterility

0.2 μM filtered

Production

Purified from tissue culture supernatant in an animal free facility

Purification

Protein G

Molecular Weight

150 kDa

RRID

AB_2819055

Storage

The antibody solution should be stored at the stock concentration at 4°C. Do not freeze.


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[#BE0329]InVivoMAb anti-mouse CD71 (TfR1)